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单志东,吕新厅,李英杰,黄仁俊,应小俊,李宁,吕志良,周鹏.腹腔镜与开腹胃十二指肠溃疡穿孔修补术临床效果对比及对患者WBC、CRP和PCT影响[J].浙江中西医结合杂志,2017,27(9):
腹腔镜与开腹胃十二指肠溃疡穿孔修补术临床效果对比及对患者WBC、CRP和PCT影响
Comparison of clinical effects between laparoscopic and open repair of gastroduodenal ulcer perforation and its effects on WBC, CRP and PCT
投稿时间:2017-02-17  修订日期:2017-04-17
DOI:
中文关键词:  腹腔镜  开腹  胃十二指肠溃疡穿孔修补术  效果  WBC  CRP  PCT
英文关键词:Laparoscopy  open  gastroduodenal ulcer perforation repair  effect  WBC  CRP  PCT
基金项目:
作者单位E-mail
单志东 永康市第一人民医院 shanzhidong6671@163.com 
吕新厅 永康市第一人民医院 普通外科二 321300  
李英杰 永康市第一人民医院 普通外科二 321300  
黄仁俊 永康市第一人民医院 普通外科二 321300  
应小俊 永康市第一人民医院 普通外科二 321300  
李宁 永康市第一人民医院 普通外科二 321300  
吕志良 永康市第一人民医院 普通外科二 321300  
周鹏 永康市第一人民医院 普通外科二 321300  
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中文摘要:
      目的:探讨腹腔镜与开腹胃十二指肠溃疡穿孔修补术临床效果对比及对患者WBC、CRP和PCT的影响。方法:选自我院于2015年5月~2016年12月期间收治的胃十二指肠溃疡急性穿孔行穿孔修补手术患者60例,按照随机数字表法分为腹腔镜组30例与开腹组30例。腹腔镜组采用腹腔镜胃十二指肠溃疡穿孔修补术治疗,开腹组采用开腹胃十二指肠溃疡穿孔修补术治疗。比较两组手术时间、术中出血量、切口长度、住院时间、胃肠功能恢复时间、自主下床活动时间、术后并发症及术前和术后WBC、CPR、PCT变化。结果:腹腔镜组手术时间短于开腹组,术中出血量少于开腹组,切口长度小于开腹组,住院时间短于开腹组,均有统计学差异(P<0.05);腹腔镜组胃肠功能恢复时间和自主下床活动时间优于开腹组,且术后并发症少于开腹组,均有统计学差异(P<0.05);两组术后WBC、CRP及PCT均增加,但腹腔镜术后明显低于开腹组,均有统计学差异(P<0.05)。结论:腹腔镜胃十二指肠溃疡穿孔修补术临床效果优于开腹组,且对WBC、CRP和PCT的影响小,具有重要研究意义。
英文摘要:
      Objective: To investigate the clinical effect of laparoscopic and open repair of gastroduodenal ulcer perforation and the influence of WBC, CRP and PCT. Methods: 60 patients with acute perforation of gastroduodenal ulcer treated in our hospital from May 2015 ~ December 2016 were selected and divided into laparoscopic group 30 cases and open group 30 cases according to the random number table method. The laparoscopic group was treated with laparoscopic repair of gastroduodenal ulcer perforation, and laparotomy group was treated with open repair of gastroduodenal ulcer perforation. The operation time, intraoperative blood loss, length of incision, length of stay, recovery time of gastrointestinal function, independent ambulation time, postoperative complications and changes of WBC, CPR and PCT before and after operation were compared between the two groups. Results: the operative time of laparoscopic group was shorter than the open group , intraoperative bleeding was less than the open group , the incision length is less than the open group , the hospitalization time is shorter than the open group (P<0.05); laparoscopic group gastrointestinal function recovery time and independent ambulation time than open group , postoperative complications and less than open group (P<0.05); WBC, CRP and PCT were increased after operation in the two groups, but after laparoscopic surgery was significantly lower than the open group (P<0.05). Conclusion: the clinical effect of laparoscopic repair of gastroduodenal ulcer perforation is better than that of the open group, and has little influence on WBC, CRP and PCT.
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